Transmission Electron Microscope (TEM)  JEOL JEM-F200

Specifications:

Electron Gun: Cold Field Emiistion Gun(CFEG)

Specimen Holder: Single Tilt Holder; Double Tilt Holder; Three Sample Holder

EDS: JED2300T Super X-Ray System

Supporting Pre-processing System: Zeiss FIB, LeicaTXP, UC7FC7, RES102

Accelerating Voltage: 20-200kV(Standard 80kV, 200kV)

TEM Lattice Resolution:200kV 0.1nm; 80kV 0.14 nm

TEM Specimen Drift: ＜1nm/min

STEM HAADF Resolution: 200kV  0.136nm; 80kV  0.31nm

STEM BF Resolution:200kV  0.136nm; 80kV  0.31nm

EDS Resolution: ＜129eV

Function:

TEM, HRTEM, STEM, HAADF, SAED,  EDS test for the different kind of sample. At least one dimession of  the sample should be lower than 200 nm. "

Dual Beam Electron Microscope (FIB-SEM)   Zeiss Cross Beam 350

Specifications:

Electron Gun: Thermal Electron Gun(TFEG)

Ion Source: Ga-Liquid Metal Ion Source

Detector: Chamber SE-detector and In-Lens detector for second electron imaging, aBSD1 and EsB back scattering detector

GIS: Pt and Carbon

FIB resolution at 30kV: 3.0 nm

Second Electron resolution: 1.0 nm@15KV，2.0 nm@1kV

EDS: Analytical silicon drift electric refrigeration detector for the detecting of Be4～Cf98

Cryo system: Quorum PP3005, low temperature to 190℃

Applications:

Second electron imapping, Back scattering electron imapping, X-Ray Analysis, In situ cross-section analysis, TEM sample preparation, 3D construction, Micro and Nano struction processing, 3DAP sample preparation, Cryo FIB, Cryo SEM"

Cryo-Ultramicrotomes Cryo-Ultramicrotomes    Leica EM UC7/FC7

Specifications:

Knives: Diatome ultramicrotomy; Diatome cryo diamond knife; Diatome trim diamond knife

Knife making system: EM KMR3 for glass knife making

Section Thickness: 1nm-15μm

Section size: 0.2-14 mm

Speed: 0.05-100mm/s

Working Temperature: -15℃-  -185℃

Applications:

High quality sectioning of specimens for light, electron, and atomic force microscopy examination.

Gas Chromatography/Quadrupole-Time of Flight Mass Spectrometry

 GC/Q-TOF MS    Agilent 8890-7250

Specifications:

Retention time reproducibility:＜0.008%

Ion Source:Low Energy EI

Quadrupole Isolation Mass Range：m/z 20-1050

TOF Mass Accuracy :<2ppm for 1 pg OFN at m/z 271.9867

TOF Mass Range:m/z 20-3000

TOF Mass Resolution (FWHM): > 25,000 at m/z 271.9867 independent of acquisition rate

Typical applications:

Target quantification,suspicious screening and non-targeted screening for food and flavoring analysis(Nitrosamine carcinogens, etc),environmental analysis(Polycyclic aromatic hydrocarbons, pesticides, etc)，industrial chemicals analysis(chlorinated hydrocarbons, etc),Oil industry analysis(Gasoline, volatile sulfur-containing compounds, etc) and pharmaceutical analysis."

X-ray diffractometer 

XRD    PANalytical Empyrean powder diffractometer

The anode material is Cu, with K-Alpha1, K-Alpha1, and K-Beta values of 1.54060, 1.54443, and 1.39225 Å. The current and voltage during the test are 40 mA and 45 kV.

Scanning angle range: -6 °~163 °, scanning speed: 0.1 °~50 °/min; Fixed Anti-scatter Slits: 1 °, 1/2 °, 1/4 °, 1/8 °, 1/16 °.

Sample changer 15 positions .

Beta-filter Ni.

Stage flat samples.

Reflection-transmission spinner.

Confocal laser scanning microscope

 CLSM  Olympus，FV3000

Used for morphology and fluorescence quantitative analysis of 2D/3D (XYZ)/4D (XYZT) for non-destructive analysis of tissues, cells, bacteria, and thin sections。

Laser:405nm、488nm、561nm、640nm

 Objective：1.25X、10X、20X、40X、60XO、100XO

Liquid Chromatography Mass Spectrometry LCMS 

LC：ThermoFisher Vanquish/ThermoFisher UltiMate 3000 RSLCnano

MS:ThermoFisher Orbitrap Exploris 240

Resolution powers:240000

Mass range:m/z40-6000

Scan speed:30Hz

Typical applications:Biopharmaceutical characterization, proteomics, metabolomics, lipidomics, food and environmental research, clinical research"

Isotope ratio mass spectrometer IRMS  

Thermo Scientific™ DELTA V Advantage IRMS

Thermo Scientific™ DELTA V Advantage IRMS

 Its sensitivity for CO2 in Dual Inlet mode is better than 1200 molecules per ion. The standard collector configuration is the Universal Triple Collector. H2 collectors with on-line hydrogen capability are optional. The DELTA V Advantage delivers high performance in Dual Inlet and Continuous Flow mode. Excellent linearity is guaranteed with or without helium carrier gas flow.

Connecting the Elemental Analyzer FLASH IRMS to an Isotope Ratio Mass Spectrometer allows for two-element analysis of C and N or H and O with a dynamic range greater than 1:1000.

The Thermo Scientific GC IsoLink TRACE 1310with combustion and high temperature pyrolysis is used for compound specific isotope analysis of complex mixtures separated on a capillary GC column. Determination of D/H, 13C/12C, 15N/14N and 18O/16O isotope ratios is possible for all mixtures accessible by the GC technique. 

IRMS is used with GasBench II foratmospheric trace-gas research in the ppm and ppb range.

Flow cytometer FCM    BECKMAN COULTER CytoFLEX

Laser:375nm、405nm、488nm、638nm、561nm、808nm

Minimum sample volume：≤10ul

Dynamic linear range of the signal:≥7-decade dynamic range

Speed of analysis:≥3000 cell/sec

Fluorescence sensitivity:FITC≤30MESF、PE≤10MESF

Typical applications:Immunophenotyping、Cell Sorting、Cell Cycle Analysis、Apoptosis、Cell Proliferation Assays、Intracellular Calcium Flux"

High resolution stable isotope mass spectrometry 

Panorama  NU AMETEK Panorama

The Panorama, takes a completely new ion optical approach for these type of instruments, and is based on the ESA – Quadrupole – Magnet  design of Matsuda. Optimised for ultra-high resolution studies, whilst maintaining  high sensitivity, this design uses a magnet of 800mm radius, and has been shown to resolve all the methane peaks at mass 18amu, to permit the first truly sub permille measurement of, not only 13CH3D, but also 12CH2D2. The mass dispersion / magnification figure of merit for this instrument is 1400mm.

X-ray Photoelectron Spectroscopy  

XPS  Brand:PHI

Model:PHI Versaprobe 4

Function:Dual beam charge neutralization;Argon ion gun, cluster ion gun ;Inert atmosphere transfer tubes.etc.XPS is widely used to analyze qualitative and quantitative analysis of inorganic compounds, alloys, semiconductors, polymers, elements, catalysts, glass, ceramics, dyes, paper, inks, wood, cosmetics, biomaterials, compound valence analysis, in-depth analysis of materials."

X-ray Microscopy/Computed Tomography

XRM/ X-ray CT   ZEISS Xradia 610 Versa

higest Resolution: 0.5 μm

X-ray Source: Voltage Range: 30 – 160 kV; Maximum Output: 25 W

Objectives: 0.4x, 4x, 20x

The 3D X-ray microscope enables non-destructive imaging of internal structures with high resolution. It offers detailed external and internal 3D imaging, allowing for precise analysis of materials, defects, and microstructures in various fields such as materials science, biology, and geology etc."

Nano particle size and zeta potential analyzer

  DLS  Brand:Anton Paar 

Model:Litesizer 500

Function：The basic principle of dynamic light scattering measurement of nanoparticles is based on the Brownian motion of nanoparticles. Smaller particles move at a higher speed than larger particles. The hydrodynamic diameter of the particles can be determined by measuring the speed of the particles."

Gas Adsorption Analyzer  

BET  Brand:Anton Paar 

Model:Autosorb-iQ

Function：For key substances involved in the fields of drying, catalysis, liquid purification, gas storage, respiratory protection, pollution control, etc., physical adsorption is the core to achieve their functionality. To achieve these functions, these materials need to have corresponding characteristics in terms of structural characteristics, including specific surface area, porosity, pore size, pore volume, adsorption heat, adsorption kinetics, etc. Among them, specific surface area, pore size, pore volume, etc. are the most commonly used characterization parameters"

Continuous flow analyzer 

CFA  Brand:Seal 

Model:AA 500

Function:Detection of phosphate, ammonium salt, nitrate, nitrite and silicate in water, wastewater, plants, soil extracts, seawater, tobacco, feed, and fertilizers."

Nano Secondary Ion Mass Spectrometer NanoSIMS  

Brand：Cameca     Model：NanoSIMS 50L

The NanoSIMS is a unique ion microprobe that allows the analysis of elemental and isotopic composition of a solid sample at a sub-micron spatial resolution. It delivers simultaneously key performance metrics include high analysis spatial resolution, high transmission, and high sensitivity. It is mainly used in astrochemistry, geochemistry, microbiology, cell biology, and materials science. It provides information about the lateral distribution of elements and its isotopes as well as the quantitative information about the isotopic composition of a sample."

High pressure freezing & freezing substitution system  

HPF & FS  Brand： Leica

Model：EM ICE, EM AFS2

High pressure freezing is key for the study of intricate changes in fine structure or cellular dynamics. Currently cryo-fixation is the only way to fix cellular constituents without introducing significant structural alterations. It can cryo-immobilize aqueous samples under high pressure with a unique freezing principle and uncover secrets of the cellular process. The EM ICE solution uses a unique, alcohol-free freezing principle to allow a superior cryo-fixation of the specimen enabling better quality results to be obtained."

Multi-collectoer Inductively coupled plasma mass spectrometry 

 MC-ICP-MS  Brand: Thermo Fisher Scientific

Modle: Neptune XT

Function: MC-ICP-MS combine the Ar ICP-source of conventional ICP-MS instruments with the magnetic sector analyser and multiple-Faraday cup array of TIMS. It can be used to analyze the isotope ratios of most elements in the periodic table, such as lithium, strontium, copper and Zinc."

laser ablation system  LA  Brand: Elemental Scientific Lasers

Modle: NWR193HE

Function: The laser ablation system is a widely used analytical technique for for in-situ micro analysis of solid samples, combined with ICP-MS to determine element content, and combined with MC-ICP-MS to determine the isotopic composition. High sensitivity, good dynamic range of more than ten orders of magnitude and minimal sample preparation made this technique popular in environment, biology and particularly geosciences."

Ion Chromatography Inductively Coupled Plasma Mass Spectrometry IC-ICP-MS 

IC: Themo Fisher ICS 6000

Ion Chromatography (IC) is a powerful analytical technique used for separating and quantifying ions in a sample. 

ICP MS: Themo Fisher iCAP RQ

Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is an extremely sensitive analytical technique used for detecting and quantifying trace elements at very low concentrations, typically in the parts-per-billion (ppb) or parts-per-trillion (ppt) range. 

IC-ICP-MS is a powerful hyphenated technique that combines Ion Chromatography (IC) with Inductively Coupled Plasma Mass Spectrometry (ICP-MS).